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Overcoming a
Fundamental Constraint
in Human Health

A team of passionate individuals on a mission to achieve healthy longevity.

Mission

Develop therapies that reverse vascular calcification to restore arterial elasticity and eliminate the burden of cardiovascular disease. 

Vision

A world where longevity is defined by resilience across the human lifespan, not by stiffness, vascular failure, and loss of blood flow. 

Operating Principles

Operating

Principles

01

Biological solutions over conventional symptom treatment, even when it challenges prevailing practice. 

02

Molecular precision over broad exposure: interventions that act where they are needed, not everywhere at once.

03

Institutional rigor: apply standards that meet or exceed expectations of top-tier academic and industry partners.

04

Platform thinking: systems that can scale across indications, partners, and geographies.

Our Leadership

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Shyam Parekh, Ph.D., MBA

Chief Executive Officer

Shyam Parekh, Ph.D., MBA

Chief Executive Officer

Experienced leader with decades in corporate strategy, business development, line management, scientific research, and market intelligence
Managed full life cycles of 20+ complex corporate development initiatives (Kimberly-Clark Healthcare, Halyard Health, Avanos Medical)
Business advisor for NIH/VA C3i Program, oversight committee member for Biolocity Fund, and founder of growth advisory consulting firm

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Prof. Narendra Vyavahare, Ph.D.​

Co-Founder & Chief Scientific Officer

Prof. Narendra Vyavahare, Ph.D.​

Founder & Chief Scientific Officer

Co-founder of four biotech companies: 1 commercial, 1 in clinical trials, 2 in pre-clinical
Hunter Endowed Chair & Professor of Bioengineering at Clemson University; Director of NIH-funded SC BioCRAFT Center
Pioneer in cardiovascular biomaterials; developed clinically used heart valve calcification treatments
Fellow of AIMBE with 25+ years of continuous NIH funding

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Douglas Mulhall

Co-Founder

Douglas Mulhall

Co-Founder

30 years’ experience developing biocompatible products with multinational companies and governments. Co-developed ISO and other global standards 
Former founding CEO of ICTV; former MD of EPEA Scientific Institute; Co-founder of O Instituto Ambientale, Brazil
Bestselling author on calcification and elastin. Researcher affiliated with 4 universities; currently at Technical University of Munich with 350+ citations

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Valentin Busch

Co-founder & Head of Operations

Valentin Busch

Co-founder & Head of Operations

Engineering leader with 8+ years scaling teams and delivering regulated products in biotech (ISO 27001, GMP, FDA Title 21 CFR part 11).

B.Sc. Biomedical Engineering; MedTec Startup School graduate focusing on lean startup methodology in healthcare. Founded & led businesses across Europe, USA, & Australia.

First investor in Elastrin and sourced key relationship leading to further $12.5M in funding.

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Scientific Advisory Board 

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Dr. Giulio Guagliumi, MD

Interventional Cardiologist

Advisor

Dr. Giulio Guagliumi, MD

Interventional Cardiologist

Advisor

International leader in OCT-guided coronary interventions; validated OCT with histopathology for stent-vessel assessment.
Former President, Italian Society of Invasive Cardiology; Co-Chair, EAPCI Scientific Program for ESC Congress; Fellow, European Society of Cardiology since 2004.
Author of 300+ peer-reviewed manuscripts.

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Dr. Sagar S. Gandhi, MD

FACS, RPVI ​

Advisor

Dr. Sagar S. Gandhi, MD

FACS, RPVI ​

Advisor

Distinguished Clinical Leadership: Co-Director of Prisma Health Aortic Center, leading multidisciplinary care for complex aortic pathologies and endovascular interventions.
Clinical Associate Professor (Vascular Surgery, USC SOM Greenville) and Clinical Assistant Professor (Biomedical Engineering, Clemson),.
Author of 20+ peer-reviewed publications.

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Dr. Christopher Bates, MD, Ph.D.​

Vascular Surgeon, Prisma Health

Advisor

Dr. Christopher Bates, MD, Ph.D.​

Vascular Surgeon, Prisma Health

Advisor

PhD in Biomedical Sciences (molecular neuroscience) and an MD.
Board-certified General Surgeon; completing specialized fellowship in Vascular Surgery at Prisma Health.
Authored multiple publications,  research spans molecular signaling, breast cancer therapy, and COVID-19-related thromboembolic events

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Gerhard Hager, Ph.D.

Founder NCD Co. ​

Consulting Expert

Gerhard Hager, Ph.D.

Founder NCD Co. ​

Consulting Expert

Non-clinical development expert with extensive experience in design and management of preclinical programs integrating research, pharmacology, ADME and toxicology. Broad expertise in early drug development ranging from small molecules to biologics, vaccines to ATMPs.
Today director of The NCD Company that provides non-clinical drug development services to the pharmaceutical industry.

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Dr. Aloke Finn

President & CSO CVPath Institute Inc.

Consulting Expert

Dr. Aloke Finn

President & CSO CVPath Institute Inc.

Consulting Expert

President and Chief Scientific Officer at CVPath Institute since 2024.
Former Assistant Professor of Medicine at Emory University, directing NIH- and AHA-funded basic and translational cardiovascular research.
Author of 100+ peer-reviewed articles, editorials, and reviews impacting cardiovascular science and clinical medicine.

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Dr. Bruce H. Gray, MS, DO

FSVM, FACOI, FSCAI​

Consulting Expert

Dr. Bruce H. Gray, MS, DO

FSVM, FACOI, FSCAI​

Consulting Expert

Emeritus Professor of Surgery & Vascular Medicine at USC School of Medicine Greenville; Founder of Gray Vascular LLC.
Former Director of Endovascular Services at Prisma Health.
Editorial boards member of Annals of Vascular Surgery, Endovascular Today.
Past President, American Board of Vascular Medicine; Co-Chair of SCAI’s Peripheral Disease Committee.

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Dr. Francisco Ujueta

MD, MS, RPVI, FAHA, FACC, FACP

Consulting Expert

Dr. Francisco Ujueta

MD, MS, RPVI, FAHA, FACC, FACP

Consulting Expert

Dr. Francisco Ujueta is a physician-scientist with expertise in cardiovascular and vascular medicine, clinical, and environmental research. Currently an Assistant Professor at Vanderbilt University Medical Center, he brings extensive clinical, academic, and research experience, with a focus on developing innovative therapies for cardiovascular disease, peripheral artery disease, and environmental risk factors.

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We are moving beyond temporary fixes toward a future of true tissue rejuvenation.

Anchored by Leading Institutions. 

Elastrin's science and development are supported by collaborations with NIH, Clemson University, BIO, and additional academic and translational partners. 

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